Scaling Behavior of Maximal Repeat Distributions in Genomic Sequences: A Randomize Test Follow Up Study

نویسنده

  • J. D. Wang
چکیده

In our previous study (Wang et al., 2008) it is found that the relative frequency distribution of maximal repeat sequencesLog(P(k)) versus the frequency of appearance Log(k) exhibits scaling behavior, i.e. P(k) ~ k-γ. In order to valid the above findings are not due to an artifact, we redone the study by performing the randomize test, and reanalysis the results by plotting the relative frequency of maximal repeat patterns against the rank of the appearance. The rank plots give a better coefficient of determination values than our previous work, i.e. using frequency plot. The rank plot study is motivated by Li et al. (Li et al. 2005). The work gave a rigorous presentation on the theory of scale-free graphs, and it is pointed out that size-rank plot is more reliable than size-frequency plot. In section 2, we give a description of the randomize test procedures. Section 3 is the power-law study results. Section 4 is the summary and discussion. AbstrAct

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Scaling Behavior of Maximal Repeat Distributions in Genomic Sequences : A Randomize Test

Despite the fact that the origin of software agent systems has been rooted in autonomous artificial intelligence and cognitive psychology, their implementations are still based on conventional imperative computing techniques rather than autonomous computational intelligence. This paper presents a cognitive informatics perspective on autonomous agent systems (AAS’s). A hierarchical reference mod...

متن کامل

Data Mining for Identification of Forkhead Box O (FOXO3a) in Different Organisms Using Nucleotide and Tandem Repeat Sequences

 Background: Deregulation of FOXO3a gene which belongs to Forkhead box O (FOXO) transcription factors, can cause cancer (e.g. breast cancer). FOXO factors have important role in ubiquitination, acetylation, de-acetylation, protein-protein interactions and phosphorylation. Understanding the regulation and mechanisms of FOXO3a can lead to cancer treatment. The aim of this study recent association...

متن کامل

Genetic Variation of Informative Short Tandem Repeat (STR) Loci in an Iranian Population

In the present study, genotyping of six short tandem repeat (STR) loci including CSF1PO, D16S539, F13A01, F13B, LPL and HPRTB was performed on genomic DNA from 127 unrelated individuals from the Iranian province of Isfahan. The results indicated that the allele and genotype distributions were in accordance with Hardy-Weinberg expectations. The observed heterozygosity (Ho), expected heterozygosi...

متن کامل

Relationship between segmental duplications and repeat sequences in human chromosome 7.

Various types of repeat sequences are abundant in genomic sequences, and they are associated with the biological phenomena at distinct levels. In particular, comparative analyses of whole-genome-sized sequence data have revealed that repeat sequences cause segmental duplications, which are a type of chromosomal structural arrangement. In this study, we analyzed the relationships between segment...

متن کامل

The effectiveness of cognitive behavior stress management on functional dyspepsia symptoms

Introduction: Functional dyspepsia and digestive disorders arecommon, debilitating and costly. Little information is availableabout the role of stress management in terms of cognitivebehavioraltreatment of dyspepsia. The purpose of this studywas to investigate the effectiveness of cognitive-behavioral stressmanagement on functional dyspepsia symptoms in patients whoreferred to digestion clinics...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013